Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662242 | 0.94 | MAPT (0.52) | L3MBTL1MBTD1L3MBTL3MAPTNPC1 | |
| SCHEMBL12919 | 0.94 | MAPT (0.52) | L3MBTL1MBTD1L3MBTL3MAPTNPC1 | |
| SCHEMBL13056 | 0.94 | MAPT (0.52) | L3MBTL1MBTD1L3MBTL3MAPTNPC1 | |
| SCHEMBL27764172 | 0.87 | L3MBTL1 (0.55) | L3MBTL1MBTD1L3MBTL3MAPTNPC1 | |
| SCHEMBL12449707 | 0.86 | NOTUM (0.55) | L3MBTL1MBTD1L3MBTL3MAPTNPC1 | |
| SCHEMBL12449705 | 0.86 | NOTUM (0.55) | L3MBTL1MBTD1L3MBTL3MAPTNPC1 | |
| SCHEMBL12839 | 0.86 | NOTUM (0.55) | L3MBTL1MBTD1L3MBTL3MAPTNPC1 | |
| SCHEMBL6220618 | 0.82 | MAPT (0.56) | L3MBTL1L3MBTL3MAPTNPC1RAB9A | |
| SCHEMBL26326854 | 0.78 | MAPT (0.49) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL26326846 | 0.78 | MAPT (0.49) | MAPTNPC1RAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765099-B2 | STAT6 inhibitors | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-09-19 | — | — | US | disclosed |