Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | ITGAL | P20701 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19364755 | 0.90 | HRH3 (0.48) | HRH3HRH4SLC6A5ITGB2ICAM1 | |
| SCHEMBL888751 | 0.86 | ITGB2 (0.47) | HRH3HRH4ITGB2ICAM1ITGAL | |
| SCHEMBL10122812 | 0.86 | ITGB2 (0.47) | HRH3HRH4ITGB2ICAM1ITGAL | |
| SCHEMBL12979930 | 0.81 | ITGB2 (0.47) | HRH3HRH4SLC6A5ITGB2ICAM1 | |
| SCHEMBL6806998 | 0.81 | ITGB2 (0.62) | SLC6A5ITGB2ICAM1ITGAL | |
| SCHEMBL13187470 | 0.81 | ITGB2 (0.49) | HRH3HRH4SLC6A5ITGB2ICAM1 | |
| SCHEMBL8906903 | 0.78 | HRH3 (0.47) | HRH3HRH4SLC6A5ITGB2ICAM1 | |
| SCHEMBL17750695 | 0.77 | HRH3 (0.40) | HRH3HRH4SLC6A5ITGB2ICAM1 | |
| SCHEMBL15691407 | 0.77 | HRH3 (0.40) | HRH3HRH4SLC6A5ITGB2ICAM1 | |
| SCHEMBL14961161 | 0.73 | ITGB2 (0.49) | HRH3HRH4SLC6A5ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765087-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2017-09-19 | — | — | US | disclosed |