Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23982216 | 0.84 | CA12 (0.39) | CA12CA2CA9CA1 | |
| SCHEMBL20003079 | 0.80 | CA12 (0.37) | CA12CA2CA9CA1MLYCD | |
| SCHEMBL8073515 | 0.80 | CA12 (0.46) | CA12CA2CA9CA1TSHR | |
| SCHEMBL5208268 | 0.77 | CA12 (0.46) | CA12CA2CA9CA1MLYCD | |
| SCHEMBL25790978 | 0.77 | CA12 (0.38) | CA12CA2CA9CA1MLYCD | |
| SCHEMBL5208263 | 0.76 | CA12 (0.45) | CA12CA2CA9CA1MLYCD | |
| SCHEMBL24850726 | 0.74 | CA12 (0.33) | CA12CA2CA9CA1 | |
| SCHEMBL26450616 | 0.73 | ALDH1A1 (0.39) | CA12CA2CA9CA1 | |
| SCHEMBL18843199 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL29210355 | 0.73 | CA12 (0.46) | CA12CA2CA9CA1MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765087-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2017-09-19 | — | — | US | disclosed |