Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.56 |
| ▸ | HIF1AN | Q9NWT6 | 4/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16694375 | 0.93 | HIF1A (0.66) | ODC1HIF1AHSP90AA1HIF1AN | |
| SCHEMBL16867649 | 0.93 | HIF1A (0.66) | ODC1HIF1AHSP90AA1HIF1AN | |
| SCHEMBL16694376 | 0.93 | HIF1A (0.66) | ODC1HIF1AHSP90AA1HIF1AN | |
| SCHEMBL16865517 | 0.91 | HIF1A (0.57) | ODC1HIF1AHSP90AA1HIF1ANACHE | |
| SCHEMBL19286788 | 0.80 | HIF1A (0.82) | ODC1HIF1AHSP90AA1HIF1ANACHE | |
| SCHEMBL19365878 | 0.79 | HIF1A (0.80) | HIF1AHSP90AA1 | |
| SCHEMBL16865516 | 0.77 | HIF1A (0.69) | HIF1AHSP90AA1 | |
| SCHEMBL29499925 | 0.75 | ODC1 (1.00) | ODC1HIF1ANACHE | |
| SCHEMBL18244646 | 0.73 | HIF1A (1.00) | HIF1AHSP90AA1 | |
| SCHEMBL16694786 | 0.73 | HIF1A (0.58) | ODC1HIF1AHSP90AA1HIF1AN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2871187-B1 | NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | SNU R&DB FOUNDATION (KR) | 2017-09-20 | — | — | EP | disclosed |