Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692394 | 0.72 | KDM4E (0.46) | KDM4EALOX15MAPK1CASP1HSD17B10 | |
| SCHEMBL31316476 | 0.70 | KDM4E (0.44) | KDM4EALOX15MAPK1CASP1HSD17B10 | |
| Bromide SCHEMBL28944789 | 0.70 | KDM4E (0.44) | KDM4EALOX15MAPK1CASP1HSD17B10 | |
| Hydrochloric Acid SCHEMBL29027490 | 0.70 | KDM4E (0.44) | KDM4EALOX15MAPK1CASP1HSD17B10 | |
| SCHEMBL18999319 | 0.68 | KDM4E (0.43) | KDM4EALOX15MAPK1CASP1HSD17B10 | |
| SCHEMBL4291299 | 0.68 | KDM4E (0.43) | KDM4EALOX15MAPK1CASP1HSD17B10 | |
| SCHEMBL19365983 | 0.68 | KDM4E (0.43) | KDM4EALOX15MAPK1CASP1HSD17B10 | |
| SCHEMBL25026160 | 0.66 | SMN1; SMN2 (0.36) | SMN1; SMN2LMNA | |
| SCHEMBL24767999 | 0.64 | HSD17B10 (0.39) | KDM4EALOX15MAPK1CASP1HSD17B10 | |
| SCHEMBL21730494 | 0.64 | NLRP3 (0.57) | KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3429355-B1 | SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS | BAYER CROPSCIENCE AG (DE) | 2020-02-05 | — | — | EP | disclosed |
| WO-2017157735-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-09-21 | — | — | WO | disclosed |