SCHEMBL19366158

SCHEMBL19366158

CCCCCCN(CCCC)CCOc1ccc(CCCC/N=C(\N)NC(=O)c2nc(Cl)c(N)nc2N)cc1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCNN1A P37088 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19361273 0.92 SCNN1A (0.69) SCNN1A
Idrevloride SCHEMBL17366462 0.90 SCNN1A (0.65) SCNN1A
SCHEMBL5671579 0.84 SCNN1A (0.86) SCNN1A
SCHEMBL18596853 0.84 SCNN1A (0.51) SCNN1A
SCHEMBL15093001 0.84 SCNN1A (0.51) SCNN1A
SCHEMBL16572096 0.82 SCNN1A (0.53) SCNN1A
SCHEMBL22334860 0.81 SCNN1A (0.54) SCNN1A
Hydrochloric Acid SCHEMBL1961465 0.81 SCNN1A (0.79) SCNN1A
SCHEMBL916744 0.80 SCNN1A (0.76) SCNN1A
SCHEMBL17919076 0.80 SCNN1A (0.48) SCNN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170267649-A1 STABLE SODIUM CHANNEL BLOCKERS PARION SCIENCES, INC. (US) 2017-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170267649-A1 STABLE SODIUM CHANNEL BLOCKERS SCN1B, SCN2B, CACNA1B SCNN1A 25/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.