Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 20/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1961465 | 0.89 | SCNN1A (0.79) | SCNN1A | |
| SCHEMBL916744 | 0.86 | SCNN1A (0.76) | SCNN1A | |
| 552-02 Free Base SCHEMBL2015164 | 0.86 | SCNN1A (1.00) | SCNN1A | |
| Hydrochloric Acid SCHEMBL915539 | 0.85 | SCNN1A (0.73) | SCNN1A | |
| SCHEMBL19366158 | 0.84 | SCNN1A (0.72) | SCNN1A | |
| SCHEMBL916348 | 0.83 | SCNN1A (0.94) | SCNN1A | |
| Hydrochloric Acid SCHEMBL937636 | 0.82 | SCNN1A (0.79) | SCNN1A | |
| SCHEMBL2328611 | 0.81 | SCNN1A (0.59) | SCNN1A | |
| SCHEMBL937541 | 0.81 | SCNN1A (0.74) | SCNN1A | |
| SCHEMBL2328617 | 0.80 | SCNN1A (0.56) | SCNN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485360-A4 | SODIUM CHANNEL BLOCKERS | PARION SCIENCES INC (US) | 2006-07-05 | — | — | EP | disclosed |
| EP-1485360-A2 | SODIUM CHANNEL BLOCKERS | Johnson, Michael R. (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003070182-A2 | SODIUM CHANNEL BLOCKERS | JOHNSON MICHAEL R (US) | 2003-08-28 | — | — | WO | disclosed |