Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | PPARD | Q03181 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 6/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6122515 | 1.00 | AKR1B1 (0.34) | AKR1B1PPARGPPARDPPARAGPR84 | |
| SCHEMBL3029047 | 1.00 | AKR1B1 (0.34) | AKR1B1PPARGPPARDPPARAGPR84 | |
| SCHEMBL2108728 | 0.92 | GPR84 (0.40) | PPARGPPARDPPARAGPR84HDAC11 | |
| Palmoxirate SCHEMBL1579204 | 0.92 | GPR84 (0.40) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL2110326 | 0.92 | GPR84 (0.40) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL11464015 | 0.92 | GPR84 (0.40) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL2109685 | 0.92 | GPR84 (0.40) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL2109983 | 0.92 | GPR84 (0.40) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL2108730 | 0.92 | GPR84 (0.40) | PPARGPPARDPPARAGPR84HDAC11 | |
| SCHEMBL2110319 | 0.92 | GPR84 (0.40) | PPARGPPARDPPARAGPR84HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908747-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 2-HYDROXYBUTYRIC ESTER | KOWA CO (JP) | 2012-01-04 | — | — | EP | disclosed |
| US-7767845-B2 | reacting an optically active 2,3-epoxypropionic ester with a methyl Grignard reagent CH3MgX in the presence of a copper catalyst in an amount of 0.05 to 0.5 mol with respect to 1 mol of the 2,3-epoxypropionic ester; for producing pharmaceuticals, pesticides, and industrial products | KOWA CO., LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-20090209780-A1 | reacting an optically active 2,3-epoxypropionic ester with a methyl Grignard reagent CH3MgX in the presence of a copper catalyst in an amount of 0.05 to 0.5 mol with respect to 1 mol of the 2,3-epoxypropionic ester; for producing pharmaceuticals, pesticides, and industrial products | KOWA CO., LTD. (JP) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209780-A1 | reacting an optically active 2,3-epoxypropionic ester with a methyl Grignard reagent CH3MgX in the presence of a copper catalyst in an amount of 0.05 to 0.5 mol with respect to 1 mol of the 2,3-epoxypropionic ester; for producing pharmaceuticals, pesticides, and industrial products | CYP4X1, AGL, HACL2 | AKR1B1 1203/4885PPARG 1752/4885PPARD 3951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.