Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15129388 | 0.90 | PTGS2 (0.44) | PTGS2ALOX5CSF1RMAPTALOX15 | |
| SCHEMBL14428417 | 0.88 | PTGS2 (0.46) | PTGS2ALOX5CSF1RMAPTALOX15 | |
| SCHEMBL19367435 | 0.87 | KDM4E (0.47) | PTGS2CSF1RMAPTALOX15KDM4E | |
| SCHEMBL3427476 | 0.85 | PTGS2 (0.46) | PTGS2ALOX5CSF1RMAPTALOX15 | |
| SCHEMBL3426662 | 0.85 | PTGS2 (0.46) | PTGS2ALOX5CSF1RMAPTALOX15 | |
| SCHEMBL19367458 | 0.84 | PTGS2 (0.39) | PTGS2ALOX5CSF1RMAPTALOX15 | |
| SCHEMBL13932881 | 0.82 | PTGS2 (0.42) | PTGS2ALOX5CSF1RMAPTALOX15 | |
| SCHEMBL3969081 | 0.82 | SRC (0.46) | PTGS2ALOX5CSF1RMAPTALOX15 | |
| SCHEMBL1077964 | 0.81 | PTGS2 (0.45) | PTGS2ALOX5CSF1RMAPTALOX15 | |
| SCHEMBL15129543 | 0.79 | PTGS2 (0.43) | PTGS2ALOX5CSF1RMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2804855-B1 | BENZOHETEROCYCLIC COMPOUNDS AND USE THEREOF | SHANGHAI KECHOW PHARMA INC (CN) | 2017-09-20 | — | — | EP | disclosed |