Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.63 |
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076711 | 0.90 | CYP3A4 (0.67) | MAPTTP53LMNATSHRHTT | |
| SCHEMBL16903198 | 0.90 | MAPT (0.59) | MAPTTP53THRBLMNATSHR | |
| SCHEMBL16903150 | 0.87 | MAPT (0.67) | MAPTTP53LMNATSHRHTT | |
| SCHEMBL18084780 | 0.87 | MAPT (0.61) | MAPTTP53LMNATSHRHTT | |
| SCHEMBL18084763 | 0.87 | MAPT (0.61) | MAPTTP53LMNATSHRHTT | |
| SCHEMBL16903066 | 0.87 | CYP3A4 (0.54) | MAPTTP53THRBLMNATSHR | |
| SCHEMBL28454153 | 0.87 | MAPT (0.58) | MAPTTP53LMNATSHRHTT | |
| SCHEMBL28449581 | 0.87 | MAPT (0.58) | MAPTTP53LMNATSHRHTT | |
| SCHEMBL16903129 | 0.87 | MAPT (0.63) | MAPTTP53LMNATSHRHTT | |
| SCHEMBL15076704 | 0.87 | MAPT (0.55) | MAPTTP53THRBLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170266197-A1 | METHODS AND COMPOSITIONS FOR TREATING HEPATITIS B VIRUS INFECTIONS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170266197-A1 | METHODS AND COMPOSITIONS FOR TREATING HEPATITIS B VIRUS INFECTIONS | HAVCR2, HCCS, PYGL | MAPT 4168/4885TP53 811/4885THRB 1507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.