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SCHEMBL1936909

SCHEMBL1936909

CC=C(C)C1CN(C(=O)C(NC(=O)c2ccc(-c3nc(N4CCN(C)CC4)sc3F)cc2)C(C)CC)C2C(=O)COC12.CC=C(C)C1CN(C(C=O)(NC(=O)c2ccc(-c3nc(N4CCN(C)CC4)sc3F)cc2)C2CCCC2)C2C(=O)COC12

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 20/20 0.66
▸ CTSS P25774 9/20 0.66
▸ CTSL P07711 7/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3132470 0.92 CTSK (0.67) CTSKCTSSCTSL
SCHEMBL1146992 0.90 CTSK (0.67) CTSKCTSSCTSL
SCHEMBL1146707 0.90 CTSK (0.80) CTSKCTSSCTSL
SCHEMBL1146706 0.90 CTSK (0.80) CTSKCTSSCTSL
SCHEMBL1146995 0.90 CTSK (0.67) CTSKCTSSCTSL
SCHEMBL1146354 0.90 CTSK (0.79) CTSKCTSSCTSL
SCHEMBL1146356 0.90 CTSK (0.79) CTSKCTSSCTSL
SCHEMBL17284083 0.84 CTSK (0.61) CTSKCTSSCTSL
SCHEMBL17284084 0.84 CTSK (0.61) CTSKCTSSCTSL
SCHEMBL1146812 0.83 CTSK (0.64) CTSKCTSSCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2331548-A1 PROTEASE INHIBITORS Medivir AB (SE) 2011-06-15 — — EP disclosed
WO-2010034788-A1 PROTEASE INHIBITORS MEDIVIR AB (SE) 2010-04-01 — — WO disclosed