Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD1 | P21728 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19359398 | 1.00 | CRBN (0.59) | CRBNDRD2DRD1DRD4DRD5 | |
| SCHEMBL29923396 | 1.00 | CRBN (0.59) | CRBNDRD2DRD1DRD4DRD5 | |
| SCHEMBL19359468 | 0.95 | CRBN (0.60) | CRBNDRD2DRD1DRD4DRD5 | |
| SCHEMBL30384540 | 0.91 | CRBN (0.69) | CRBNDDB1 | |
| SCHEMBL19359504 | 0.87 | CRBN (0.57) | CRBNDDB1 | |
| SCHEMBL19370693 | 0.87 | CRBN (0.57) | CRBNDDB1 | |
| SCHEMBL29923068 | 0.87 | CRBN (0.57) | CRBNDDB1 | |
| SCHEMBL19359391 | 0.82 | CRBN (0.83) | CRBNDDB1 | |
| SCHEMBL29923644 | 0.82 | CRBN (0.83) | CRBNDDB1 | |
| SCHEMBL19370824 | 0.81 | DRD2 (0.46) | CRBNDRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017161119-A1 | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE, INC. (US) | 2017-09-21 | — | — | WO | disclosed |