Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 13/20 | 0.48 |
| ▸ | ULK1 | O75385 | 4/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.47 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | ULK2 | Q8IYT8 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442460 | 0.84 | SYK (0.53) | SYKULK1ULK2HDAC3JAK2 | |
| SCHEMBL1937742 | 0.83 | CTSC (0.49) | SYKALKINSRHDAC3JAK2 | |
| SCHEMBL1937115 | 0.80 | SYK (0.48) | SYKULK1ALKULK2HDAC3 | |
| SCHEMBL1937791 | 0.80 | CTSC (0.53) | SYKULK1ALKINSRJAK2 | |
| SCHEMBL1937720 | 0.79 | CTSC (0.48) | SYKALKINSRHDAC3JAK2 | |
| SCHEMBL2508915 | 0.78 | MAPK3 (0.47) | SYKULK1 | |
| SCHEMBL3265411 | 0.78 | AURKA (0.52) | SYKULK1ALKINSRULK2 | |
| SCHEMBL3136804 | 0.77 | JAK2 (0.65) | SYKULK1ALKINSRULK2 | |
| SCHEMBL4442456 | 0.77 | SYK (0.50) | SYKULK1ULK2HDAC3JAK2 | |
| SCHEMBL3231051 | 0.77 | ALK (0.48) | SYKULK1ALKINSRULK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331533-A1 | HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025850-A1 | HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |