Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.65 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.65 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.57 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.57 |
| ▸ | SYK | P43405 | 3/20 | 0.57 |
| ▸ | CTSC | P53634 | 4/20 | 0.53 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 4/20 | 0.51 |
| ▸ | BTK | Q06187 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.51 |
| ▸ | JAK1 | P23458 | 1/20 | 0.51 |
| ▸ | IGF1R | P08069 | 2/20 | 0.50 |
| ▸ | ULK1 | O75385 | 1/20 | 0.50 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.50 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265411 | 0.86 | AURKA (0.52) | JAK2LRRK2ALKSYKAURKA | |
| SCHEMBL2511992 | 0.84 | CTSC (0.52) | JAK2LRRK2ALKSYKCTSC | |
| SCHEMBL3150023 | 0.84 | AURKA (0.61) | JAK2SYKAURKAAURKBFLT3 | |
| SCHEMBL29816634 | 0.83 | JAK2 (0.79) | JAK2LRRK2ALKCDK19SYK | |
| SCHEMBL15391316 | 0.83 | JAK2 (0.79) | JAK2LRRK2ALKCDK19SYK | |
| SCHEMBL29695649 | 0.83 | EGFR (0.61) | JAK2LRRK2SYKTYRO3AURKA | |
| SCHEMBL4442456 | 0.83 | SYK (0.50) | JAK2SYKTYRO3AURKAJAK1 | |
| SCHEMBL4442460 | 0.83 | SYK (0.53) | JAK2SYKTYRO3AURKAJAK1 | |
| SCHEMBL3135192 | 0.82 | SYK (0.56) | JAK2SYKAURKAJAK1TYK2 | |
| SCHEMBL1937742 | 0.81 | CTSC (0.49) | JAK2LRRK2ALKSYKCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081679-A1 | DIAMINOPYRIMIDINES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-04-01 | — | — | US | disclosed |
| EP-2129222-A1 | DIAMINOPYRIMIDINES AS FUNGICIDES | Bayer CropScience AG (DE) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008107096-A1 | DIAMINOPYRIMIDINES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2008-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081679-A1 | DIAMINOPYRIMIDINES AS FUNGICIDES | PM20D2, DDT, DDX41 | JAK2 1463/4885LRRK2 3855/4885ALK 880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.