Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18494037 | 1.00 | CA1 (0.33) | CA1MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL18494032 | 0.88 | BLM (0.38) | CA1LMNA | |
| SCHEMBL24221039 | 0.86 | KDM4C (0.38) | CA1LMNA | |
| SCHEMBL21166859 | 0.84 | CA1 (0.34) | CA1MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL19483467 | 0.83 | — | — | |
| SCHEMBL24221392 | 0.83 | HDAC7 (0.35) | MEN1KMT2ARAB9A | |
| SCHEMBL10166039 | 0.83 | HDAC7 (0.35) | MEN1KMT2ARAB9A | |
| SCHEMBL22215874 | 0.81 | — | — | |
| SCHEMBL21166946 | 0.81 | GABRR1 (0.40) | — | |
| SCHEMBL21216094 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017161206-A1 | CONJUGATES CONTAINING CONDITIONALLY ACTIVE ANTIBODIES OR ANTIGEN-BINDING FRAGMENTS THEREOF, AND METHODS OF USE | HALOZYME, INC. (US) | 2017-09-21 | — | — | WO | disclosed |