Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 16/20 | 0.62 |
| ▸ | BCL2A1 | Q16548 | 3/20 | 0.44 |
| ▸ | BID | P55957 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1701787 | 0.92 | BCL2 (0.67) | BCL2BCL2A1BIDMCL1BCL2L1 | |
| SCHEMBL1702284 | 0.91 | BCL2 (0.67) | BCL2BCL2A1BIDMCL1BCL2L1 | |
| SCHEMBL30314281 | 0.91 | BCL2 (0.67) | BCL2BCL2A1BIDMCL1BCL2L1 | |
| SCHEMBL19372013 | 0.89 | BCL2 (0.58) | BCL2BCL2A1BIDMCL1BCL2L1 | |
| SCHEMBL30467981 | 0.83 | BCL2 (0.67) | BCL2BCL2A1BIDMCL1BCL2L1 | |
| SCHEMBL1701846 | 0.83 | BCL2 (0.67) | BCL2BCL2A1BIDMCL1BCL2L1 | |
| SCHEMBL1701772 | 0.82 | BCL2 (0.68) | BCL2BCL2A1BIDMCL1BCL2L1 | |
| SCHEMBL31450632 | 0.79 | BCL2 (0.61) | BCL2BCL2A1BIDMCL1BCL2L1 | |
| SCHEMBL26648191 | 0.79 | BCL2 (0.61) | BCL2BCL2A1BIDMCL1BCL2L1 | |
| SCHEMBL31450744 | 0.78 | BCL2A1 (0.63) | BCL2BCL2A1BIDMCL1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4218731-A2 | MELT-EXTRUDED SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT | AbbVie Ireland Unlimited Company (IE) | 2023-08-02 | — | — | EP | disclosed |
| EP-2613769-B1 | MELT-EXTRUDED SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT | ABBVIE IRELAND UNLIMITED CO (IE) | 2017-09-27 | — | — | EP | disclosed |