Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 19/20 | 0.67 |
| ▸ | BID | P55957 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1701846 | 1.00 | BCL2 (0.67) | BCL2BIDMCL1BCL2A1BCL2L1 | |
| SCHEMBL1701772 | 0.94 | BCL2 (0.68) | BCL2BIDMCL1BCL2A1BCL2L1 | |
| SCHEMBL30314281 | 0.92 | BCL2 (0.67) | BCL2BIDMCL1BCL2A1BCL2L1 | |
| SCHEMBL1702284 | 0.92 | BCL2 (0.67) | BCL2BIDMCL1BCL2A1BCL2L1 | |
| SCHEMBL31450632 | 0.87 | BCL2 (0.61) | BCL2BIDMCL1BCL2A1BCL2L1 | |
| SCHEMBL26648191 | 0.87 | BCL2 (0.61) | BCL2BIDMCL1BCL2A1BCL2L1 | |
| SCHEMBL1701787 | 0.87 | BCL2 (0.67) | BCL2BIDMCL1BCL2A1BCL2L1 | |
| SCHEMBL19372012 | 0.83 | BCL2 (0.62) | BCL2BIDMCL1BCL2A1BCL2L1 | |
| SCHEMBL30314080 | 0.81 | BCL2 (1.00) | BCL2 | |
| SCHEMBL1701523 | 0.81 | BCL2 (1.00) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4474383-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | AbbVie Ireland Unlimited Company (IE) | 2024-12-11 | — | — | EP | disclosed |
| EP-4218731-A2 | MELT-EXTRUDED SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT | AbbVie Ireland Unlimited Company (IE) | 2023-08-02 | — | — | EP | disclosed |