Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Moroxydine SCHEMBL2945594 | 0.78 | LMNA (1.00) | LMNASMN1; SMN2ALDH1A1KMT2ACA12 | |
| Moroxydine SCHEMBL19038555 | 0.78 | LMNA (1.00) | LMNASMN1; SMN2ALDH1A1KMT2ACA12 | |
| Moroxydine SCHEMBL7952575 | 0.76 | LMNA (0.96) | LMNASMN1; SMN2ALDH1A1KMT2ACA12 | |
| SCHEMBL7963478 | 0.75 | LMNA (0.53) | LMNAMAPTSMN1; SMN2ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL15537612 | 0.75 | LMNA (0.70) | LMNASMN1; SMN2ALDH1A1KMT2ACA12 | |
| Moroxydine SCHEMBL16011670 | 0.73 | LMNA (0.88) | LMNASMN1; SMN2ALDH1A1KMT2ACA12 | |
| SCHEMBL27218189 | 0.69 | LMNA (0.47) | LMNASMN1; SMN2ALDH1A1KMT2ACA12 | |
| Hydrochloric Acid SCHEMBL15537745 | 0.69 | LMNA (0.61) | LMNAMAPTSMN1; SMN2ALDH1A1CA12 | |
| SCHEMBL12002589 | 0.69 | LMNA (0.61) | LMNASMN1; SMN2ALDH1A1KMT2ACA12 | |
| SCHEMBL22347892 | 0.69 | LMNA (0.61) | LMNASMN1; SMN2ALDH1A1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332925-A1 | NOVEL DIHYDROTRIAZINE DERIVATIVE | Hamari Chemicals, Ltd. (JP) | 2011-06-15 | — | — | EP | disclosed |