Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17394575 | 0.79 | — | — | |
| SCHEMBL5046225 | 0.73 | GAA (0.43) | PDE3BPDE3A | |
| Quinoline SCHEMBL28196613 | 0.70 | PARP1 (0.62) | PARP1 | |
| SCHEMBL792475 | 0.68 | — | — | |
| SCHEMBL31152915 | 0.68 | PARP1 (0.47) | PARP1 | |
| SCHEMBL1266263 | 0.68 | PARP1 (0.34) | PARP1 | |
| SCHEMBL1938772 | 0.68 | PARP1 (0.47) | PARP1 | |
| Hydrochloric Acid SCHEMBL26625860 | 0.67 | — | — | |
| SCHEMBL442572 | 0.67 | PARP1 (0.37) | PARP1 | |
| SCHEMBL33931 | 0.66 | PARP1 (0.95) | PARP1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172126-A1 | LIBRARIES OF PEPTIDE CONJUGATES AND METHODS FOR MAKING THEM | XENOME LTD (AU) | 2011-07-14 | — | — | US | disclosed |
| EP-2331561-A1 | LIBRARIES OF PEPTIDE CONJUGATES AND METHODS FOR MAKING THEM | Xenome Ltd (AU) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025510-A1 | LIBRARIES OF PEPTIDE CONJUGATES AND METHODS FOR MAKING THEM | XENOME LTD (AU) | 2010-03-11 | — | — | WO | disclosed |