Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21499666 | 0.93 | P2RX3 (0.43) | P2RX3 | |
| SCHEMBL20432337 | 0.88 | P2RX3 (0.46) | P2RX3 | |
| SCHEMBL19375462 | 0.88 | P2RX3 (0.46) | P2RX3 | |
| SCHEMBL18834374 | 0.84 | P2RX3 (0.38) | P2RX3 | |
| SCHEMBL20656224 | 0.83 | P2RX3 (0.46) | P2RX3 | |
| SCHEMBL21316331 | 0.83 | P2RX3 (0.45) | P2RX3 | |
| SCHEMBL19375479 | 0.83 | P2RX3 (0.43) | P2RX3 | |
| SCHEMBL21499689 | 0.79 | PDE5A (0.41) | P2RX3 | |
| SCHEMBL21316333 | 0.78 | P2RX3 (0.40) | P2RX3 | |
| SCHEMBL19505466 | 0.78 | P2RX3 (0.39) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B3 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2018-08-01 | — | — | EP | disclosed |
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |