Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.57 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16028066 | 0.91 | TRPC5 (0.68) | TRPC4TRPC5KCNH2TRPC1MAPK1 | |
| SCHEMBL16028760 | 0.90 | TRPC4 (0.57) | TRPC4TRPC5KCNH2TRPC1MAPK1 | |
| SCHEMBL16028400 | 0.90 | TRPC4 (0.59) | TRPC4TRPC5KCNH2TRPC1MAPK1 | |
| SCHEMBL16028333 | 0.87 | TRPC5 (0.68) | TRPC4TRPC5KCNH2TRPC1MAPK1 | |
| SCHEMBL16028502 | 0.86 | TRPC4 (0.57) | TRPC4TRPC5KCNH2TRPC1MAPK1 | |
| SCHEMBL16028585 | 0.86 | TRPC5 (0.67) | TRPC4TRPC5KCNH2TRPC1MAPK1 | |
| SCHEMBL16364012 | 0.86 | TRPC5 (0.55) | TRPC4TRPC5KCNH2TRPC1MAPK1 | |
| SCHEMBL16028428 | 0.86 | TRPC5 (0.64) | TRPC4TRPC5KCNH2TRPC1MAPK1 | |
| SCHEMBL16076034 | 0.86 | TRPC5 (0.66) | TRPC4TRPC5KCNH2TRPC1MAPK1 | |
| SCHEMBL19375229 | 0.86 | TRPC5 (0.66) | TRPC4TRPC5KCNH2TRPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |