Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 17/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.42 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.42 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16028322 | 0.92 | P2RX3 (0.52) | P2RX3LMNAMAPTTRPC1TRPC4 | |
| SCHEMBL18834594 | 0.85 | P2RX3 (0.51) | P2RX3LMNAMAPTTRPC1TRPC4 | |
| SCHEMBL18833876 | 0.85 | P2RX3 (0.53) | P2RX3LMNAMAPTTRPC4TRPC5 | |
| SCHEMBL18022800 | 0.85 | P2RX3 (0.45) | P2RX3LMNAMAPTTRPC1TRPC4 | |
| SCHEMBL16364301 | 0.84 | P2RX3 (0.53) | P2RX3LMNAMAPT | |
| SCHEMBL16028658 | 0.84 | P2RX3 (0.51) | P2RX3LMNAMAPTTRPC4TRPC5 | |
| SCHEMBL16028518 | 0.84 | P2RX3 (0.51) | P2RX3LMNAMAPTTRPC4TRPC5 | |
| SCHEMBL19375417 | 0.84 | P2RX3 (0.52) | P2RX3LMNAMAPTTRPC4TRPC5 | |
| SCHEMBL16028107 | 0.84 | TSHR (0.54) | P2RX3LMNAMAPTTRPC4TRPC5 | |
| SCHEMBL16028309 | 0.84 | P2RX3 (0.54) | P2RX3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |