Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 14/20 | 0.61 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.61 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16028131 | 0.91 | TRPC5 (0.70) | TRPC5TRPC4TRPC1KCNH2LMNA | |
| SCHEMBL16028504 | 0.88 | TRPC5 (0.69) | TRPC5TRPC4TRPC1KCNH2LMNA | |
| SCHEMBL16027677 | 0.85 | TRPC5 (0.74) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL16027848 | 0.85 | TRPC5 (0.69) | TRPC5TRPC4TRPC1KCNH2LMNA | |
| SCHEMBL16028767 | 0.84 | TRPC5 (0.85) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL16027658 | 0.84 | TRPC5 (0.81) | TRPC5TRPC4TRPC1KCNH2LMNA | |
| SCHEMBL16028349 | 0.83 | TRPC5 (0.66) | TRPC5TRPC4TRPC1KCNH2LMNA | |
| SCHEMBL19375046 | 0.83 | TRPC5 (0.71) | TRPC5TRPC4TRPC1KCNH2PCSK9 | |
| SCHEMBL19375572 | 0.82 | TRPC5 (0.59) | TRPC5TRPC4TRPC1KCNH2LMNA | |
| SCHEMBL16028601 | 0.82 | TRPC5 (0.79) | TRPC5TRPC4TRPC1KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-09-20 | — | — | EP | disclosed |