Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.60 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19381302 | 0.90 | ALDH1A1 (0.52) | HTR6LRRK2ALDH1A1KDM4EMEN1 | |
| SCHEMBL19381334 | 0.90 | MEN1 (0.53) | HTR6LRRK2ALDH1A1KDM4EMEN1 | |
| SCHEMBL19381661 | 0.90 | MEN1 (0.53) | HTR6LRRK2ALDH1A1KDM4EMEN1 | |
| SCHEMBL19381655 | 0.90 | MEN1 (0.53) | HTR6LRRK2ALDH1A1KDM4EMEN1 | |
| SCHEMBL19381657 | 0.90 | MEN1 (0.53) | HTR6LRRK2ALDH1A1KDM4EMEN1 | |
| SCHEMBL19381141 | 0.90 | MEN1 (0.53) | HTR6LRRK2ALDH1A1KDM4EMEN1 | |
| SCHEMBL19381163 | 0.90 | MEN1 (0.53) | HTR6LRRK2ALDH1A1KDM4EMEN1 | |
| SCHEMBL19381525 | 0.89 | KDM4E (0.53) | HTR6LRRK2ALDH1A1KDM4EMEN1 | |
| SCHEMBL19381660 | 0.89 | ALDH1A1 (0.53) | HTR6LRRK2ALDH1A1KDM4EMEN1 | |
| SCHEMBL19381666 | 0.89 | ALDH1A1 (0.53) | HTR6LRRK2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017159484-A1 | 2,4-DIAMINOPHENOL DERIVATIVE, AND AGENT FOR INHIBITING AGGREGATION OF TAU AND/OR AMYLOID β | 学校法人同志社 | 2017-09-21 | — | — | WO | disclosed |