Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 9/20 | 0.46 |
| ▸ | MMP9 | P14780 | 7/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148825 | 0.88 | PSMB5 (0.53) | USP30MMP2MMP9ADAMTS4ALDH1A1 | |
| SCHEMBL15195203 | 0.87 | MMP2 (0.45) | USP30MMP2MMP9ADAMTS4ALDH1A1 | |
| SCHEMBL2507489 | 0.84 | PSMB5 (0.51) | MMP2MMP9ADAMTS4ALDH1A1NPY5R | |
| SCHEMBL19347782 | 0.84 | MMP2 (0.46) | USP30MMP2MMP9ADAMTS4ALDH1A1 | |
| SCHEMBL3135693 | 0.80 | PSMB5 (0.55) | MMP2MMP9ADAMTS4NPY5RF2 | |
| SCHEMBL16459707 | 0.80 | MMP2 (0.47) | MMP2MMP9ADAMTS4ALDH1A1NPY5R | |
| SCHEMBL15832305 | 0.79 | MMP2 (0.43) | MMP2MMP9ADAMTS4ALDH1A1NPY5R | |
| SCHEMBL15195219 | 0.79 | MMP2 (0.43) | MMP2MMP9ADAMTS4ALDH1A1NPY5R | |
| SCHEMBL3149645 | 0.78 | PSMB5 (0.51) | USP30MMP2MMP9ADAMTS4NPY5R | |
| SCHEMBL15195208 | 0.78 | MMP2 (0.48) | MMP2MMP9ADAMTS4ALDH1A1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346882-B1 | DERIVATIVES OF 1-AMINO-2-CYCLOBUTYLETHYLBORONIC ACID | MILLENNIUM PHARM INC (US) | 2017-09-20 | — | — | EP | disclosed |