Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.30 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.30 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.30 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2181537 | 1.00 | MAPT (0.48) | MAPTCYP3A4CYP19A1GRM2MAPK1 | |
| SCHEMBL10666518 | 0.92 | MAPT (0.53) | MAPTCYP3A4CYP19A1MAPK1CYP26A1 | |
| SCHEMBL10666511 | 0.92 | MAPT (0.53) | MAPTCYP3A4CYP19A1MAPK1CYP26A1 | |
| SCHEMBL10664395 | 0.82 | MAPT (0.60) | MAPTCYP3A4CYP19A1CYP26A1CYP1A2 | |
| SCHEMBL10664398 | 0.82 | MAPT (0.60) | MAPTCYP3A4CYP19A1CYP26A1CYP1A2 | |
| SCHEMBL1937809 | 0.82 | MEN1 (0.43) | MAPTCYP19A1MAPK1HSP90AA1KMT2A | |
| SCHEMBL2181209 | 0.82 | MEN1 (0.43) | MAPTCYP19A1MAPK1HSP90AA1KMT2A | |
| SCHEMBL1936250 | 0.82 | MAPT (0.47) | MAPTCYP3A4CYP19A1CYP26A1CYP1A2 | |
| SCHEMBL2179492 | 0.82 | MAPT (0.47) | MAPTCYP3A4CYP19A1CYP26A1CYP1A2 | |
| SCHEMBL10666615 | 0.74 | MAPT (0.55) | MAPTCYP3A4CYP19A1GRM2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110166021-A1 | Imidazole and Triazole Compounds, the Use Thereof and Preparations Containing These Compounds | BASF SE (DE) | 2011-07-07 | — | — | US | disclosed |
| EP-2331509-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, THE USE THEREOF AND PREPARATIONS CONTAINING THESE COMPOUNDS | BASF SE (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010028986-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, THE USE THEREOF AND PREPARATIONS CONTAINING THESE COMPOUNDS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166021-A1 | Imidazole and Triazole Compounds, the Use Thereof and Preparations Containing These Compounds | NISCH, CYP3A5, CYP11B2 | MAPT 505/4885CYP3A4 6/4885CYP19A1 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.