Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.63 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.63 |
| ▸ | PHF8 | Q9UPP1 | 10/20 | 0.57 |
| ▸ | KDM5A | P29375 | 3/20 | 0.56 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.55 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17604512 | 0.81 | KDM4C (0.63) | KDM4CKDM2BPHF8KDM5AKDM5B | |
| SCHEMBL19383012 | 0.78 | PHF8 (0.67) | KDM4CKDM2BPHF8KDM5AKDM5B | |
| SCHEMBL24244174 | 0.78 | PHF8 (0.67) | KDM4CKDM2BPHF8KDM5AKDM5B | |
| SCHEMBL17898921 | 0.77 | KDM4C (0.67) | KDM4CKDM2BPHF8KDM5AKDM5B | |
| SCHEMBL16034053 | 0.77 | KDM4C (1.00) | KDM4CKDM2BPHF8KDM5AKDM5B | |
| SCHEMBL16033447 | 0.77 | PHF8 (0.58) | KDM4CKDM2BPHF8KDM5AKDM5B | |
| SCHEMBL24244193 | 0.76 | PHF8 (0.61) | KDM4CKDM2BPHF8KDM5AKDM5B | |
| SCHEMBL17604650 | 0.75 | KDM4C (0.63) | KDM4CKDM2BPHF8KDM5AKDM5B | |
| SCHEMBL18949661 | 0.74 | KDM4C (0.62) | KDM4CKDM2BPHF8KDM5AKDM5B | |
| SCHEMBL17604647 | 0.74 | KDM4C (0.65) | KDM4CKDM2BPHF8KDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017161033-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-09-21 | — | — | WO | disclosed |