Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.55 |
| ▸ | KDM5A | P29375 | 3/20 | 0.55 |
| ▸ | KDM2B | Q8NHM5 | 6/20 | 0.53 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 3/20 | 0.35 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19383511 | 0.92 | KDM4C (0.54) | PHF8KDM4CKDM5AKDM2BKDM5B | |
| SCHEMBL16034379 | 0.87 | PHF8 (0.71) | PHF8KDM4CKDM5AKDM2BKDM5B | |
| SCHEMBL19383406 | 0.86 | KDM4C (0.57) | PHF8KDM4CKDM5AKDM2BKDM5B | |
| SCHEMBL19383188 | 0.82 | KDM4C (0.60) | PHF8KDM4CKDM5AKDM2BKDM5B | |
| SCHEMBL17604560 | 0.79 | KDM4C (0.70) | PHF8KDM4CKDM5AKDM2BKDM5B | |
| SCHEMBL24244249 | 0.78 | KDM4C (0.56) | PHF8KDM4CKDM5AKDM2BKDM5B | |
| SCHEMBL16033671 | 0.78 | KDM4C (0.70) | PHF8KDM4CKDM5AKDM2BKDM5B | |
| SCHEMBL19383315 | 0.77 | KDM4C (0.54) | PHF8KDM4CKDM5AKDM2BKDM5B | |
| SCHEMBL17604553 | 0.75 | KDM4C (0.73) | PHF8KDM4CKDM5AKDM2BKDM5B | |
| SCHEMBL24244170 | 0.74 | KDM4C (0.61) | PHF8KDM4CKDM5AKDM2BKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193881-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2022-02-09 | — | — | EP | disclosed |
| WO-2017161033-A1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2017-09-21 | — | — | WO | disclosed |