SCHEMBL19385446

SCHEMBL19385446

CC(=O)OC(O)(CO)CO

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.42
ALDH1A1 P00352 3/20 0.33
TSHR P16473 1/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL907982 0.74 GAA (0.44) GAAALDH1A1TSHRLMNAHSD17B10
SCHEMBL29090047 0.72
SCHEMBL30370576 0.72 GAA (0.38) GAA
SCHEMBL29021120 0.70 ALDH1A1 (0.52) GAAALDH1A1LMNAHSD17B10KDM4E
Ammonia Solution, Strong SCHEMBL4621896 0.70 GAA (0.46) GAAALDH1A1TSHRLMNAHSD17B10
SCHEMBL11031201 0.69
SCHEMBL7262556 0.69 ALDH1A1 (0.42) GAAALDH1A1TSHRLMNAHSD17B10
SCHEMBL6936981 0.69 GAA (0.44) GAAALDH1A1TSHRLMNAHSD17B10
SCHEMBL7080423 0.67
SCHEMBL19042338 0.67 GAA (0.38) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017164750-A1 THERAPEUTIC COMPOSITIONS AND USES THEREOF MANUKA HEALTH NEW ZEALAND LIMITED (NZ) 2017-09-28 WO disclosed