Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11754025 | 0.89 | BCHE (0.47) | BCHEACHETSHRTP53POLB | |
| SCHEMBL4848123 | 0.82 | NCF1 (0.50) | TSHRTP53POLBGAANCF1 | |
| SCHEMBL11762958 | 0.81 | PDE5A (0.49) | TSHRTP53POLBGAANCF1 | |
| SCHEMBL4848300 | 0.80 | POLB (0.54) | TP53POLBGAANCF1HTR1A | |
| Nitric Acid SCHEMBL11753412 | 0.80 | KDM4E (0.42) | BCHEACHETP53POLBGAA | |
| Nitric Acid SCHEMBL11753422 | 0.80 | KDM4E (0.42) | BCHEACHETP53POLBGAA | |
| SCHEMBL1234357 | 0.79 | NCF1 (0.55) | BCHETP53NCF1HTR1ADRD2 | |
| SCHEMBL6619950 | 0.78 | RAD52 (0.59) | TOP2ATP53POLBNCF1HTR1A | |
| SCHEMBL3956730 | 0.77 | TLR8 (0.56) | BCHETP53NCF1HTR1ADRD2 | |
| SCHEMBL2452998 | 0.77 | KDM4E (0.62) | TP53POLBGAANCF1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017165489-A1 | ANTIVIRAL AGENTS FOR TREATING ZIKA AND DENGUE VIRUS INFECTIONS | EMORY UNIVERSITY (US) | 2017-09-28 | — | — | WO | claimed |