Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.51 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AMD1 | P17707 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5034807 | 0.81 | HSPA8 (0.55) | ADORA2AADORA3PDE4DPDE3APDE2A | |
| SCHEMBL14075810 | 0.81 | HSPA8 (0.55) | ADORA2AADORA3PDE4DPDE3APDE2A | |
| SCHEMBL5034818 | 0.81 | HSPA8 (0.55) | ADORA2AADORA3PDE4DPDE3APDE2A | |
| SCHEMBL19387123 | 0.80 | PI4KA (0.72) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL7202481 | 0.80 | PI4KA (0.72) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL14075797 | 0.80 | PI4KA (0.72) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL14088982 | 0.80 | PI4KA (0.72) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL19387129 | 0.80 | PI4KA (0.72) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL572470 | 0.80 | PI4KA (0.72) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL18159460 | 0.80 | PI4KA (0.72) | PI4KAPI4K2BPI4K2API4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771390-B2 | Process for the preparation of regadenoson | SCINOPHARM TAIWAN, LTD. (TW) | 2017-09-26 | — | — | US | disclosed |