Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24943509 | 0.93 | CYP4F2 (0.51) | CYP4F2CYP4A11ALDH1A1ATMHTR2C | |
| SCHEMBL20180944 | 0.93 | CYP4F2 (0.51) | CYP4F2CYP4A11ALDH1A1ATMHTR2C | |
| SCHEMBL15371643 | 0.91 | CYP4F2 (0.47) | CYP4F2CYP4A11ALDH1A1ATMHTR2C | |
| SCHEMBL19359962 | 0.89 | CYP4F2 (0.52) | CYP4F2CYP4A11ALDH1A1ATMNAAA | |
| SCHEMBL27898238 | 0.88 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1HTR2CNAAA | |
| SCHEMBL27362196 | 0.88 | CYP4F2 (0.50) | CYP4F2CYP4A11ALDH1A1HTR2CNAAA | |
| SCHEMBL27204893 | 0.85 | CYP4F2 (0.53) | CYP4F2CYP4A11ALDH1A1NAAATSHR | |
| SCHEMBL19018809 | 0.85 | CYP4F2 (0.52) | CYP4F2CYP4A11ALDH1A1ATMNAAA | |
| SCHEMBL15780654 | 0.84 | CYP4F2 (0.61) | CYP4F2CYP4A11ALDH1A1ATMNAAA | |
| Ammonia Solution, Strong SCHEMBL28636353 | 0.84 | CYP4F2 (0.51) | CYP4F2CYP4A11ALDH1A1NAAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9770519-B2 | Protein-polymer-drug conjugates | MERSANA THERAPEUTICS, INC. (US) | 2017-09-26 | — | — | US | disclosed |