Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24943509 | 1.00 | CYP4F2 (0.51) | CYP4F2CYP4A11NAAAHTR2CELANE | |
| SCHEMBL27362196 | 0.95 | CYP4F2 (0.50) | CYP4F2CYP4A11NAAAHTR2CMEN1 | |
| SCHEMBL27898238 | 0.95 | CYP4F2 (0.50) | CYP4F2CYP4A11NAAAHTR2CMEN1 | |
| SCHEMBL19387397 | 0.93 | CYP4F2 (0.46) | CYP4F2CYP4A11NAAAHTR2CELANE | |
| SCHEMBL29146085 | 0.90 | CYP4F2 (0.58) | CYP4F2CYP4A11NAAAELANEMAPT | |
| SCHEMBL4809521 | 0.90 | CYP4F2 (0.58) | CYP4F2CYP4A11NAAAELANEMAPT | |
| SCHEMBL1490324 | 0.90 | CYP4F2 (0.58) | CYP4F2CYP4A11NAAAELANEMAPT | |
| SCHEMBL28673377 | 0.90 | CYP4F2 (0.58) | CYP4F2CYP4A11NAAAELANEMAPT | |
| SCHEMBL23581670 | 0.90 | CYP4F2 (0.58) | CYP4F2CYP4A11NAAAELANEMAPT | |
| SCHEMBL6686460 | 0.90 | CYP4F2 (0.58) | CYP4F2CYP4A11NAAAELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180140716-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180140716-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | PBRM1, STAMBP, TSPO | CYP4F2 3509/4885CYP4A11 4630/4885NAAA 3020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.