Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2757955 | 0.80 | CYP1A2 (0.69) | CA1CA2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1484349 | 0.79 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2C9RAB9APOLB | |
| SCHEMBL19133623 | 0.78 | CA1 (0.59) | CA1CA2HPGDANO1KDM4E | |
| SCHEMBL19387994 | 0.78 | RAB9A (0.58) | CA1CA2HPGDANO1KDM4E | |
| SCHEMBL25434734 | 0.76 | HDAC6 (0.52) | CYP1A2CYP3A4CYP2C9KDM4E | |
| SCHEMBL16891683 | 0.76 | GAA (0.39) | CYP1A2CYP3A4HPGDCYP2C9L3MBTL1 | |
| SCHEMBL16886387 | 0.75 | HCAR2 (0.37) | CYP1A2CYP3A4CYP2C9RAB9AMAPT | |
| SCHEMBL25404860 | 0.74 | HTT (0.41) | CYP1A2CYP3A4CYP2C9KDM4ELMNA | |
| SCHEMBL19387992 | 0.74 | CA1 (0.48) | CA1CA2CYP1A2CYP3A4HPGD | |
| SCHEMBL8240261 | 0.73 | HPGD (0.71) | CA1CA2HPGDANO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771320-B2 | Carbocyclic sulfone RORγ modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-26 | — | — | US | disclosed |