Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12295869 | 1.00 | HPGD (0.46) | HPGDMAPTLMNARAB9AL3MBTL1 | |
| SCHEMBL20221517 | 0.86 | KMT2A (0.46) | HPGDMAPTLMNARAB9AL3MBTL1 | |
| SCHEMBL21501031 | 0.82 | FFAR1 (0.57) | MAPTL3MBTL1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL23425326 | 0.82 | FFAR1 (0.57) | MAPTL3MBTL1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL31596805 | 0.79 | SMN1; SMN2 (0.53) | HPGDMAPTLMNARAB9AKMT2A | |
| SCHEMBL3222423 | 0.77 | HDAC8 (0.50) | HPGDMAPTLMNARAB9AL3MBTL1 | |
| SCHEMBL50646 | 0.77 | MAPT (0.68) | HPGDMAPTLMNARAB9AL3MBTL1 | |
| SCHEMBL13790981 | 0.77 | MAPT (0.35) | HPGDMAPTLMNARAB9AL3MBTL1 | |
| SCHEMBL11803963 | 0.77 | KMT2A (0.43) | HPGDMAPTLMNARAB9AL3MBTL1 | |
| SCHEMBL11703625 | 0.77 | KMT2A (0.43) | HPGDMAPTLMNARAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9770439-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-26 | — | — | US | disclosed |