SCHEMBL50646

SCHEMBL50646

CC(=O)c1ccc(C(C)=O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.68
RAB9A P51151 5/20 0.68
HPGD P15428 4/20 0.68
LMNA P02545 2/20 0.68
L3MBTL1 Q9Y468 2/20 0.68
KMT2A Q03164 2/20 0.68
SMN1; SMN2 Q16637 3/20 0.65
HSD17B1 P14061 1/20 0.65
MAPK1 P28482 3/20 0.59
NOS3 P29474 2/20 0.59
NOS1 P29475 2/20 0.59
NPC1 O15118 4/20 0.56
ALDH1A1 P00352 1/20 0.56
STAT3 P40763 1/20 0.56
STAT1 P42224 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
GAA P10253 1/20 0.54
TAAR1 Q96RJ0 1/20 0.52
STS P08842 1/20 0.52
KDM4E B2RXH2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL5533098 0.93 MAPT (0.75) MAPTRAB9AHPGDLMNAL3MBTL1
Acetic Acid SCHEMBL28009208 0.93 MAPT (0.67) MAPTRAB9AHPGDLMNAL3MBTL1
SCHEMBL11441494 0.90 MAPT (0.80) MAPTRAB9AHPGDLMNAL3MBTL1
SCHEMBL197130 0.90 MAPT (0.80) MAPTRAB9AHPGDLMNAL3MBTL1
SCHEMBL27475366 0.90 MAPT (0.59) MAPTRAB9AHPGDLMNAL3MBTL1
SCHEMBL23691954 0.90 MAPT (0.59) MAPTRAB9AHPGDLMNAL3MBTL1
SCHEMBL15339369 0.90 CES2 (0.60) MAPTRAB9AHPGDLMNAL3MBTL1
SCHEMBL131397 0.90 LMNA (0.60) MAPTRAB9AHPGDLMNAL3MBTL1
SCHEMBL14211973 0.90 CES2 (0.60) MAPTRAB9AHPGDLMNAL3MBTL1
SCHEMBL55409 0.87 SMN1; SMN2 (0.74) MAPTRAB9AHPGDLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4577 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3746309-B1 HEAT-SENSITIVE RECORDING MATERIAL MITSUBISHI HITEC PAPER EUROPE GMBH (DE) 2026-01-28 EP claimed
US-12454144-B2 Heat-sensitive recording material comprising phenol-free organic colour developers MITSUBISHI HITEC PAPER EUROPE GMBH (DE) 2025-10-28 US claimed
CN-119926191-B Conjugated microporous organic solvent-resistant nanofiltration composite membrane and preparation method and application thereof 中山大学 2025-06-13 CN claimed
CN-119926191-A Conjugated microporous organic solvent-resistant nanofiltration composite membrane and preparation method and application thereof 中山大学 2025-05-06 CN claimed
EP-4370579-B1 HARDENER FOR EPOXIDE RESINS SIKA TECH AG (CH) 2025-04-09 EP claimed
US-20250084206-A1 HARDENER FOR EPOXY RESINS SIKA TECHNOLOGY AG (CH) 2025-03-13 US claimed
US-12121852-B2 Apparatus comprising a contaminant-resistant and non-corrosive desiccant composite with high moisture capacity W. L. GORE & ASSOCIATES, INC. (US) 2024-10-22 US claimed
CN-118684552-A Method for direct trifluoromethyl of electron-deficient aromatic ring 武汉软件工程职业学院(武汉开放大学) 2024-09-24 CN claimed
US-12042385-B2 Compositions and methods for treating bone fractures ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2024-07-23 US claimed
US-12024594-B2 Multifunctional materials for temporary bonding BREWER SCIENCE, INC. (US) 2024-07-02 US claimed
US-4120909-A DEHYDRATION OF METHYL PHENYL KETONES, CATALYST HERCULES INCORPORATED (US) 1978-10-17 US claimed
US-4115231-A Crosslinkable mixtures of oligomers or polymers and diamines CIBA-GEIGY CORPORATION (US) 1978-09-19 US claimed
US-4111771-A CROSSLINKABLE TETRA-IMIDYL DERIVATIVES AND CROSSLINKED POLYMERS THEREFROM CIBA-GEIGY CORPORATION (US) 1978-09-05 US claimed
US-4110188-A CROSSLINKABLE MIXTURES OF BIS-IMIDYL DERIVATIVES CIBA-GEIGY CORPORATION (US) 1978-08-29 US claimed
US-4092331-A FROM A POLYHYDRIC PHENOL CONTAINING TWO PAIR ORTHO HYDROXY GROUPS AND A KETONE OR ACETAL, LEWIS ACID CATALYST S.A. TEXACO BELGIUM N.V. (BE) 1978-05-30 US claimed
US-4076537-A Light-sensitive materials containing organo tellurium or selenium compounds and sensitizers FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US claimed
US-4036818-A Method of preparing polymers of polyphenylene type KORSHAK VASILY VLADIMIROVICH 1977-07-19 US claimed
US-4000187-A THERMAL STABILITY, COATINGS, CAST FILMS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1976-12-28 US claimed
US-3970579-A Low melting liquid-crystal mixtures OWENS-ILLINOIS, INC. (US) 1976-07-20 US claimed
US-3950431-A EXTRACTION WITH A SOLUTION OF AN ALCOHOL AND SODIUM HYDROXIDE OR SODIUM CARBONATE SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-04-13 US claimed