Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19388790 | 0.83 | CHRM1 (0.32) | TSHR | |
| SCHEMBL19388624 | 0.77 | FFAR3 (0.40) | — | |
| SCHEMBL16407791 | 0.77 | FFAR3 (0.32) | TSHR | |
| SCHEMBL19115843 | 0.74 | MME (0.33) | TSHR | |
| SCHEMBL24261243 | 0.74 | FFAR3 (0.32) | TSHR | |
| SCHEMBL16391436 | 0.73 | ALDH1A1 (0.30) | — | |
| SCHEMBL19388129 | 0.72 | ALDH1A1 (0.35) | — | |
| SCHEMBL19388617 | 0.70 | MME (0.33) | TSHR | |
| SCHEMBL19388488 | 0.70 | MEN1 (0.30) | TSHR | |
| SCHEMBL16409162 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9770439-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-26 | — | — | US | disclosed |