Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 14/20 | 0.61 |
| ▸ | MAT2A | P31153 | 2/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670763 | 0.88 | ENPP2 (0.73) | ENPP2AKR1B1PTGDR2MAPK8PPARG | |
| SCHEMBL671880 | 0.84 | ENPP2 (0.62) | ENPP2AKR1B1PTGDR2MAPK8 | |
| SCHEMBL19389468 | 0.77 | ENPP2 (0.60) | ENPP2MAT2AAKR1B1PTGDR2MAPK8 | |
| SCHEMBL19750181 | 0.76 | ENPP2 (0.74) | ENPP2AKR1B1PTGDR2MAPK8 | |
| SCHEMBL670421 | 0.76 | ENPP2 (1.00) | ENPP2MAT2AAKR1B1PTGDR2MAPK8 | |
| SCHEMBL14127915 | 0.76 | ENPP2 (0.80) | ENPP2AKR1B1PTGDR2MAPK8 | |
| SCHEMBL19389444 | 0.76 | ENPP2 (0.49) | ENPP2MAT2AAKR1B1PTGDR2 | |
| SCHEMBL14668191 | 0.75 | ENPP2 (0.73) | ENPP2AKR1B1PTGDR2MAPK8 | |
| SCHEMBL19389431 | 0.74 | ENPP2 (0.56) | ENPP2MAT2AAKR1B1PTGDR2 | |
| SCHEMBL19389486 | 0.74 | ENPP2 (0.49) | ENPP2MAT2AAKR1B1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606031-B1 | AUTOTAXIN INHIBITORS AND USES THEREOF | AMIRA PHARMACEUTICALS INC (US) | 2017-09-27 | — | — | EP | disclosed |