Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.34 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.34 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.32 |
| ▸ | CXCL10 | P02778 | 1/20 | 0.32 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.32 |
| ▸ | CCL2 | P13500 | 1/20 | 0.32 |
| ▸ | CCL5 | P13501 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19390475 | 1.00 | CYP3A4 (0.42) | CYP3A4MAPTCYP2C9CYP2C19MAPK1 | |
| SCHEMBL26257060 | 1.00 | CYP3A4 (0.42) | CYP3A4MAPTCYP2C9CYP2C19MAPK1 | |
| SCHEMBL10261606 | 1.00 | CYP3A4 (0.42) | CYP3A4MAPTCYP2C9CYP2C19MAPK1 | |
| SCHEMBL19930017 | 0.92 | CYP3A4 (0.47) | CYP3A4MAPTCYP2C9CYP2C19MAPK1 | |
| SCHEMBL19930031 | 0.90 | CYP3A4 (0.51) | CYP3A4MAPTCYP2C9CYP2C19MAPK1 | |
| SCHEMBL18086648 | 0.90 | CYP3A4 (0.51) | CYP3A4MAPTCYP2C9CYP2C19MAPK1 | |
| SCHEMBL29329389 | 0.90 | CYP3A4 (0.51) | CYP3A4MAPTCYP2C9CYP2C19MAPK1 | |
| SCHEMBL27020203 | 0.89 | MAPK1 (0.42) | CYP3A4MAPTCYP2C9CYP2C19MAPK1 | |
| SCHEMBL10262427 | 0.88 | CYP3A4 (0.42) | CYP3A4MAPTCYP2C9CYP2C19MAPK1 | |
| SCHEMBL19769264 | 0.88 | CYP3A4 (0.42) | CYP3A4MAPTCYP2C9CYP2C19MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2355658-B1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | ARBUTUS BIOPHARMA CORP (CA) | 2017-09-27 | — | — | EP | disclosed |