SCHEMBL27020203

SCHEMBL27020203

CC[C@H]1O[C@@H](OCCOCCN)[C@H](NC(C)=O)[C@@H](C)[C@H]1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.42
▸ MEN1 O00255 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ LGALS3 P17931 2/20 0.34
▸ LGALS8 O00214 1/20 0.34
▸ LGALS4 P56470 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ THRB P10828 1/20 0.34
▸ CYP3A4 P08684 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ CXCL12 P48061 2/20 0.32
▸ CXCL10 P02778 1/20 0.32
▸ CXCL8 P10145 1/20 0.32
▸ CCL2 P13500 1/20 0.32
▸ CCL5 P13501 1/20 0.32
▸ IGF2R P11717 1/20 0.32
▸ BMP2 P12643 1/20 0.30
▸ VEGFA P15692 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19390477 0.89 CYP3A4 (0.42) MAPK1MEN1KMT2ALGALS3LGALS8
SCHEMBL19390475 0.89 CYP3A4 (0.42) MAPK1MEN1KMT2ALGALS3LGALS8
SCHEMBL10261606 0.89 CYP3A4 (0.42) MAPK1MEN1KMT2ALGALS3LGALS8
SCHEMBL26257060 0.89 CYP3A4 (0.42) MAPK1MEN1KMT2ALGALS3LGALS8
SCHEMBL29330037 0.87 CYP3A4 (0.43) MAPK1MEN1KMT2ALGALS3LGALS8
SCHEMBL25746360 0.87 CYP3A4 (0.43) MAPK1MEN1KMT2ALGALS3LGALS8
SCHEMBL26257131 0.86 MAPK1 (0.37) MAPK1MEN1KMT2ALGALS3LGALS8
SCHEMBL19930017 0.82 CYP3A4 (0.47) MAPK1MEN1KMT2ALGALS3LGALS8
SCHEMBL19769332 0.81 KMT2A (0.38) MAPK1MEN1KMT2ALGALS3CYP3A4
SCHEMBL18503708 0.79 CYP3A4 (0.43) MAPK1MEN1KMT2ALGALS3LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018523-A1 GALNAC COMPOSITIONS FOR IMPROVING SIRNA BIOAVAILABILITY EMPIRICO INC. 2024-01-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018523-A1 GALNAC COMPOSITIONS FOR IMPROVING SIRNA BIOAVAILABILITY CSGALNACT1, B3GAT3, UGGT1 MAPK1 4631/4885MEN1 3283/4885KMT2A 2835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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