Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 17/20 | 0.41 |
| ▸ | EED | O75530 | 4/20 | 0.39 |
| ▸ | RBBP4 | Q09028 | 4/20 | 0.39 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.39 |
| ▸ | AEBP2 | Q6ZN18 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19390859 | 0.79 | EZH2 (0.60) | EZH2 | |
| SCHEMBL19390908 | 0.79 | EZH2 (0.60) | EZH2 | |
| SCHEMBL16402765 | 0.77 | EZH2 (0.67) | EZH2 | |
| SCHEMBL17891395 | 0.77 | EZH2 (0.67) | EZH2 | |
| SCHEMBL17891375 | 0.76 | EZH2 (0.68) | EZH2 | |
| SCHEMBL16408157 | 0.76 | EZH2 (0.68) | EZH2 | |
| SCHEMBL17789062 | 0.72 | ALDH1A1 (0.35) | EZH2 | |
| SCHEMBL17792545 | 0.71 | ALDH1A1 (0.39) | EZH2 | |
| SCHEMBL16402532 | 0.70 | EZH2 (0.52) | EZH2 | |
| SCHEMBL16402535 | 0.70 | EZH2 (0.52) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022184-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2017-09-27 | — | — | EP | disclosed |