Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19390977 | 0.93 | EZH2 (0.42) | EZH2 | |
| SCHEMBL19391031 | 0.88 | EZH2 (0.42) | EZH2 | |
| SCHEMBL19390956 | 0.85 | EZH2 (0.47) | EZH2 | |
| SCHEMBL19390905 | 0.81 | EZH2 (0.42) | EZH2 | |
| SCHEMBL15839055 | 0.80 | EZH2 (0.54) | EZH2CYP2D6CYP2C19 | |
| SCHEMBL15839065 | 0.80 | EZH2 (0.54) | EZH2CYP2D6CYP2C19 | |
| SCHEMBL19391212 | 0.79 | EZH2 (0.63) | EZH2CYP2D6CYP2C19 | |
| SCHEMBL16408169 | 0.79 | EZH2 (0.52) | EZH2CYP2D6CYP2C19 | |
| SCHEMBL16398235 | 0.79 | EZH2 (0.52) | EZH2CYP2D6CYP2C19 | |
| SCHEMBL16402311 | 0.79 | EZH2 (0.52) | EZH2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022184-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2017-09-27 | — | — | EP | disclosed |