Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 12/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19390977 | 0.87 | EZH2 (0.42) | EZH2 | |
| SCHEMBL19390941 | 0.85 | OPRM1 (0.43) | OPRM1OPRD1OPRK1CACNA1GTHRB | |
| SCHEMBL16398375 | 0.83 | OPRM1 (0.49) | OPRM1CCR4OPRD1OPRK1CACNA1G | |
| SCHEMBL16398094 | 0.83 | OPRM1 (0.50) | OPRM1CCR4OPRD1OPRK1 | |
| SCHEMBL19391031 | 0.82 | EZH2 (0.42) | EZH2 | |
| SCHEMBL19390938 | 0.81 | EZH2 (0.48) | EZH2 | |
| SCHEMBL19390963 | 0.81 | EZH2 (0.41) | EZH2 | |
| SCHEMBL16402441 | 0.80 | EZH2 (0.51) | EZH2 | |
| SCHEMBL15839169 | 0.80 | EZH2 (0.57) | EZH2 | |
| SCHEMBL16402619 | 0.80 | EZH2 (0.53) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022184-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2017-09-27 | — | — | EP | disclosed |