Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 13/20 | 0.36 |
| ▸ | EED | O75530 | 6/20 | 0.35 |
| ▸ | RBBP4 | Q09028 | 6/20 | 0.35 |
| ▸ | SUZ12 | Q15022 | 6/20 | 0.35 |
| ▸ | AEBP2 | Q6ZN18 | 6/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19390862 | 0.88 | EZH2 (0.48) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL19390966 | 0.77 | EZH2 (0.40) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL19390943 | 0.75 | EZH2 (0.45) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL19390960 | 0.72 | EZH2 (0.41) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL19390951 | 0.70 | EZH2 (0.49) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20749778 | 0.70 | EZH2 (0.47) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL19390903 | 0.70 | EZH2 (0.52) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL19391112 | 0.69 | EZH2 (0.48) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL18830306 | 0.68 | EZH2 (0.49) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20749801 | 0.68 | EZH2 (0.49) | EZH2EEDRBBP4SUZ12AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022184-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2017-09-27 | — | — | EP | disclosed |