Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 3/20 | 0.46 |
| ▸ | RBBP4 | Q09028 | 3/20 | 0.46 |
| ▸ | SUZ12 | Q15022 | 3/20 | 0.46 |
| ▸ | AEBP2 | Q6ZN18 | 3/20 | 0.46 |
| ▸ | EZH2 | Q15910 | 17/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19390951 | 0.88 | EZH2 (0.49) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL19391112 | 0.86 | EZH2 (0.48) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL19391115 | 0.83 | EZH2 (0.45) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL19390903 | 0.82 | EZH2 (0.52) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL20749820 | 0.81 | EZH2 (0.54) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL19391032 | 0.81 | EED (0.47) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL16402461 | 0.79 | EZH2 (0.50) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL19390862 | 0.79 | EZH2 (0.48) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL19390924 | 0.79 | EZH2 (0.48) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL19390930 | 0.77 | EZH2 (0.51) | EEDRBBP4SUZ12AEBP2EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022184-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2017-09-27 | — | — | EP | disclosed |