Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.38 |
| ▸ | FABP7 | O15540 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247701 | 1.00 | CYP19A1 (0.39) | CYP19A1FABP5FABP7KMT2APOLB | |
| SCHEMBL30170466 | 1.00 | CYP19A1 (0.39) | CYP19A1FABP5FABP7KMT2APOLB | |
| SCHEMBL30856517 | 1.00 | CYP19A1 (0.39) | CYP19A1FABP5FABP7KMT2APOLB | |
| SCHEMBL19371247 | 1.00 | CYP19A1 (0.39) | CYP19A1FABP5FABP7KMT2APOLB | |
| SCHEMBL26008578 | 0.92 | KMT2A (0.39) | CYP19A1FABP5FABP7KMT2ANPSR1 | |
| SCHEMBL26008577 | 0.92 | KMT2A (0.39) | CYP19A1FABP5FABP7KMT2ANPSR1 | |
| SCHEMBL25817021 | 0.88 | KMT2A (0.40) | CYP19A1FABP5FABP7KMT2AEPHX2 | |
| SCHEMBL3789335 | 0.84 | KMT2A (0.43) | FABP5FABP7KMT2APOLBEPHX2 | |
| SCHEMBL3783542 | 0.84 | KMT2A (0.43) | FABP5FABP7KMT2APOLBEPHX2 | |
| SCHEMBL3793423 | 0.84 | KMT2A (0.43) | FABP5FABP7KMT2APOLBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702451-B2 | Method for synthesizing amanitins | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2023-07-18 | — | — | US | disclosed |
| EP-3222292-A1 | AMANITIN CONJUGATES | Heidelberg Pharma GmbH (DE) | 2017-09-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702451-B2 | Method for synthesizing amanitins | CIAPIN1, AANAT, ANXA5 | CYP19A1 1102/4885FABP5 1052/4885FABP7 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.