Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 5/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 3/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.36 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.36 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19390952 | 0.86 | ALOX5 (0.41) | KDM4EEZH2ALOX5ALDH1A1MEN1 | |
| SCHEMBL19390928 | 0.85 | ALOX5 (0.40) | KDM4EEZH2ALOX5MEN1KMT2A | |
| SCHEMBL19391189 | 0.83 | EZH2 (0.43) | KDM4EEZH2ALOX5ALDH1A1MEN1 | |
| SCHEMBL19390670 | 0.80 | EZH2 (0.42) | EZH2ALOX5MEN1KMT2AMT-CO2 | |
| SCHEMBL19391004 | 0.78 | EZH2 (0.41) | EZH2ALOX5MEN1KMT2AMT-CO2 | |
| SCHEMBL19391186 | 0.77 | EZH2 (0.45) | KDM4EEZH2ALOX5ALDH1A1MEN1 | |
| SCHEMBL19391195 | 0.76 | EZH2 (0.38) | EZH2MEN1KMT2AMT-CO2ADRA1D | |
| SCHEMBL19390662 | 0.75 | EZH2 (0.40) | KDM4EMAPTEZH2ALOX5ALDH1A1 | |
| SCHEMBL19391013 | 0.75 | EZH2 (0.41) | EZH2ALOX5MEN1KMT2AMT-CO2 | |
| SCHEMBL19390913 | 0.74 | EZH2 (0.44) | KDM4EEZH2ALOX5ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022184-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2017-09-27 | — | — | EP | disclosed |