SCHEMBL19391877

C=C1[C@H](CC(C)(C)[Si](C)(C)O)C/C(=C\C=C2/CCC[C@@]3(C)C2CCC3[C@@H](C)[C@@H](C)CCC(C)(C)O[Si](CC)(CC)CC)C[C@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	VDR	P11473	11/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19391880	1.00	VDR (0.46)	VDR
SCHEMBL19391881	1.00	VDR (0.46)	VDR
SCHEMBL19391876	1.00	VDR (0.46)	VDR
SCHEMBL12332542	0.88	VDR (0.46)	VDR
SCHEMBL12332543	0.88	VDR (0.46)	VDR
SCHEMBL12332540	0.88	VDR (0.46)	VDR
SCHEMBL14510728	0.86	VDR (0.48)	VDR
SCHEMBL18059324	0.85	VDR (0.47)	VDR
SCHEMBL9070736	0.85	VDR (0.52)	VDR
SCHEMBL19158370	0.85	VDR (0.49)	VDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2556054-B1	DIASTEREOMERS OF 2-METHYLENE-19-NOR-22-METHYL-1ALPHA,25-DIHYDROXYVITAMIN D3	WISCONSIN ALUMNI RES FOUND (US)	2017-09-27	—	—	EP	disclosed