Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS9 | O00182 | 4/20 | 0.48 |
| ▸ | LGALS1 | P09382 | 4/20 | 0.48 |
| ▸ | LGALS3 | P17931 | 4/20 | 0.48 |
| ▸ | LGALS7; LGALS7B | P47929 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | SELP | P16109 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16769153 | 0.89 | LGALS9 (0.48) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLMNA | |
| SCHEMBL16769133 | 0.89 | LGALS9 (0.48) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLMNA | |
| SCHEMBL20059184 | 0.86 | POLB (0.53) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLMNA | |
| SCHEMBL19506711 | 0.83 | LGALS9 (0.43) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLMNA | |
| SCHEMBL18510855 | 0.82 | LGALS9 (0.47) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLMNA | |
| SCHEMBL17320700 | 0.82 | LGALS9 (0.46) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLMNA | |
| SCHEMBL12747029 | 0.82 | LGALS9 (0.46) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLMNA | |
| SCHEMBL18874981 | 0.82 | LGALS9 (0.46) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLMNA | |
| SCHEMBL12150955 | 0.82 | LGALS9 (0.46) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLMNA | |
| SCHEMBL25552628 | 0.81 | LGALS9 (0.43) | LGALS9LGALS1LGALS3LGALS7; LGALS7BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222628-A1 | NUCLEOSIDE PHOSPHORAMIDATES | Gilead Pharmasset LLC (US) | 2017-09-27 | — | — | EP | disclosed |