Ethacridine

Ethacridine

SCHEMBL193949

CCOc1ccc2nc3cc(N)ccc3c(N)c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
BLM P54132 2/20 1.00
TERT O14746 1/20 1.00
ABCB11 O95342 1/20 1.00
LMNA P02545 1/20 1.00
THRB P10828 1/20 1.00
CASP7 P55210 3/20 0.80
CASP1 P29466 2/20 0.80
KDM4E B2RXH2 1/20 0.80
ALDH1A1 P00352 1/20 0.80
MAPT P10636 1/20 0.80
HPGD P15428 1/20 0.80
MAPK1 P28482 1/20 0.80
HSD17B10 Q99714 1/20 0.80
APAF1 O14727 1/20 0.61
POLB P06746 1/20 0.61
CASP3 P42574 1/20 0.61
CASP6 P55212 1/20 0.61
CASP8 Q14790 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethacridine SCHEMBL30310148 1.00 MEN1 (1.00) MEN1KMT2ABLMTERTABCB11
Ethacridine SCHEMBL29456272 1.00 MEN1 (1.00) MEN1KMT2ABLMTERTABCB11
Ethacridine SCHEMBL11662539 1.00 MEN1 (1.00) MEN1KMT2ABLMTERTABCB11
Ethacridine SCHEMBL9355974 0.99 MEN1 (0.97) MEN1KMT2ABLMTERTABCB11
Ethacridine SCHEMBL30753462 0.99 MEN1 (0.97) MEN1KMT2ABLMTERTABCB11
SCHEMBL20856476 0.93 MEN1 (0.86) MEN1KMT2ABLMTERTABCB11
Ethacridine SCHEMBL7041699 0.92 MEN1 (0.85) MEN1KMT2ABLMTERTABCB11
Ethacridine SCHEMBL31197660 0.89 MEN1 (1.00) MEN1KMT2ABLMTERTABCB11
Ethacridine SCHEMBL30775016 0.89 MEN1 (1.00) MEN1KMT2ABLMTERTABCB11
Ethacridine SCHEMBL30006678 0.89 MEN1 (1.00) MEN1KMT2ABLMTERTABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3580 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025233535-A1 METHOD FOR THE DETERMINATION OF CLEAVAGE SITES IN GENOMIC DNA CAUSED BY EXPOSURE TO A SITE DIRECTED NUCLEASE ETH Zürich (CH) 2025-11-13 WO claimed
US-20250186651-A1 HYDROGEL-BASED TOPICAL WOUND DRESSING CONTAINING PROTEIN EXTRACT T&R BIOFAB CO., LTD. (KR) 2025-06-12 US claimed
EP-4543457-A1 ENTRY-MODULATING AGENTS AND USES THEREFOR Griffith University (AU) 2025-04-30 EP claimed
US-12274830-B2 Nitric oxide inhalation therapy for infants with bronchiolitis BEYOND AIR LTD (IL) 2025-04-15 US claimed
CN-119768192-A Hydrogel-based topical wound dressing comprising protein extracts 提演奥医疗科技有限公司 2025-04-04 CN claimed
CN-114129544-B Ultraviolet curable hydrogel resin for transdermal administration, hydrogel, and cataplasm comprising same Icure药品株式会社 2025-03-21 CN claimed
CN-119606646-A Manufacturing method of rivanol wet dressing based on dermatological skin injury 安徽医科大学第一附属医院 2025-03-14 CN claimed
US-12247246-B2 Identification of inhibitors of TcpC and TIR NADase activity WASHINGTON UNIVERSITY (US) 2025-03-11 US claimed
CN-119033940-A Use of PAR hydrolase inhibitors (PDD) for the treatment of peripheral neuropathies associated with DNA damage 中南大学 2024-11-29 CN claimed
CN-118533987-A Detection method for determining veterinary drug residues in food by Quechres dispersion solid phase extraction combined with HPLC-MS/MS method 成都海关技术中心 2024-08-23 CN claimed
EP-0097440-A1 Method and kit for removing and assaying complement system fragments THE UPJOHN COMPANY (US) 1984-01-04 EP claimed
US-4381239-A Method for reducing the pyrogen content of or removing pyrogens from substances contaminated therewith TANABE SEIYAKU CO., LTD. (JP) 1983-04-26 US claimed
EP-0071647-A1 PROCESS FOR RECOVERING INTERFERON GREEN CROSS CORPORATION (JP) 1983-02-16 EP claimed
EP-0003583-B1 COMPOSITIONS FOR CYTOCHEMICAL INVESTIGATION, THEIR USE AND METHOD FOR THE DETECTION OF STEROID HORMONE RECEPTORS IN HUMAN TISSUES Lee, Sin Hang (US) 1981-12-02 EP claimed
US-4254095-A GLYCOPROTEIN HORMONE-ANTIGEN COMPLEX LABELLED FOR USE AS TRACER N KIT FORM RESEARCH CORPORATION (US) 1981-03-03 US claimed
US-4215102-A Cytochemical agents and methods for the detection of steroid hormone receptors in human tissues LEE SIN H 1980-07-29 US claimed
EP-0003583-A1 Compositions for cytochemical investigation, their use and method for the detection of steroid hormone receptors in human tissues Lee, Sin Hang (US) 1979-08-22 EP claimed
US-4137307-A Process for preparing haptoglobin aqueous solution using strong anion exchanger THE GREEN CROSS CORPORATION (JP) 1979-01-30 US claimed
US-4118349-A Process for the manufacture of polystyrene latex compounds BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1978-10-03 US claimed
US-3946105-A CHROMATOGRAPHY, DIALYSIS, IMMUNIZATION, BLEEDING, ABSORPTION KOWA COMPANY, LTD. (JA) 1976-03-23 US claimed